{"id":2638,"date":"2025-07-23T10:51:38","date_gmt":"2025-07-23T08:51:38","guid":{"rendered":"https:\/\/www.saesgetters.com\/chemicals\/?p=2638"},"modified":"2025-07-25T08:47:07","modified_gmt":"2025-07-25T06:47:07","slug":"why-spf-testing-methods-matter-iso-23675-and-the-future-of-in-vitro-sunscreen-validation","status":"publish","type":"post","link":"https:\/\/www.saesgetters.com\/chemicals\/why-spf-testing-methods-matter-iso-23675-and-the-future-of-in-vitro-sunscreen-validation\/","title":{"rendered":"Why SPF testing methods matter: ISO 23675 and the future of in vitro sunscreen validation"},"content":{"rendered":"
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Why reliable SPF testing is a real challenge<\/h2> <\/div>\n <\/div>\n
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For formulators and R&D teams, developing high-performance sunscreen formulations<\/strong> is about more than selecting active ingredients \u2014 it\u2019s about proving effective, measurable protection<\/strong> under the strictest global standards<\/strong>, while balancing sensory profile, filter load, and sustainability.
\nTraditionally, the most recognized methods for measuring SPF and UVA-PF are in vivo <\/strong>protocols, such as ISO 24444:2019 (SPF) and ISO 24443:2021 (UVA-PF).<\/p>\n <\/div>\n <\/div>\n

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These methods rely on human volunteers \u2014 and in the case of SPF, involve controlled UV exposure to induce erythema (sunburn) as a means to assess protection.
\nWhile widely used, these protocols raise concerns about ethics, cost, and reproducibility \u2014 especially as the demand for cleaner, more sustainable SPF<\/strong> innovation grows across the industry.<\/p>\n <\/div>\n <\/div>\n <\/div>\n\n\n

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How the new ISO standards change the game<\/h3>

In recent years, two new standards were approved: ISO 23698 and ISO 23675.
\nBoth aim to offer an alternative to in vivo<\/strong> testing \u2014 but they work in different ways:<\/p>\n

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  • ISO 23698 still involves human volunteers but uses a more ethical approach: instead of inducing erythema, it measures the UV absorption method<\/strong> directly on treated skin.<\/li>\n
  • ISO 23675<\/strong>, the standard SAES Chemicals has chosen to adopt, is fully in vitro SPF validation<\/strong> \u2014 it works entirely on PMMA plates, with no need for volunteers at any stage.<\/li>\n<\/ul>\n

    While technically more complex, ISO 23675 is the most ethical SPF testing<\/strong> method, offering high repeatability for validating next-generation suncare innovations<\/strong>. It improves consistency and reproducibility, supporting the development of hybrid SPF<\/strong> solutions that meet global demands.<\/p>\n <\/div>\n

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    \n \n \"SAES
    <\/div> <\/div>\n <\/div>\n<\/div>\n\n\n
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    What makes ZeoSAES\u00ae UV Booster different<\/h2> <\/div>\n <\/div>\n
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    ZeoSAES\u00ae UV Booster<\/strong> is an inorganic SPF booster<\/strong> based on engineered zeolites.
    \nIt delivers measurable improvements in UV protection (+75% SPF, +38% UVA-PF at just 3% dosage)<\/strong> and is tested following the ISO 23675 in vitro<\/strong> protocol \u2014 alongside classic in vivo<\/strong> standards.<\/p>\n <\/div>\n <\/div>\n

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    This means:<\/p>\n

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    • Formulators get reliable, measurable SPF claims, validated across multiple recognized methods.<\/li>\n
    • Brands can highlight ethical SPF testing<\/strong>, aligning with modern suncare innovation<\/strong> and clean beauty<\/strong> standards.<\/li>\n
    • Your final non-nano sunscreen<\/strong> formula is more market-ready worldwide, featuring non-nano particles (<10 \u03bcm) and full global compliance (EU, US, Korea, Brazil, China).<\/li>\n<\/ul>\n <\/div>\n <\/div>\n <\/div>\n\n\n
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      Why this matters for your formulation<\/h2>

      With ZeoSAES\u00ae UV Booster, it\u2019s not just about the data \u2014 it\u2019s about flexibility and collaboration.
      \nOur lab team can run dedicated tests on your own base, helping you optimize SPF performance while reducing overall filter load, greasiness, and instability.
      \nWhether you\u2019re developing a daily sunscreen, hybrid SPF<\/strong> primer, baby care or sensitive skin SPF, the booster supports light textures and a satin-like, dry finish that both formulators and consumers expect.<\/p>\n <\/div>\n <\/div>\n

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      Global compliance and clean label<\/h3>

      High SPF, lower filters, better texture \u2014 plus full regulatory support for global markets, including China.<\/p>\n

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      • ISO 24444 (in vivo SPF<\/strong>)<\/li>\n
      • ISO 24443 (in vivo UVA-PF<\/strong>)<\/li>\n
      • ISO 23675 (in vitro SPF validation<\/strong>, PMMA-based, no human volunteers)<\/li>\n<\/ul>\n <\/div>\n<\/div>\n\n\n
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        Ready to test your next-generation sun protection?<\/h3>

        Request technical documentation, test reports or discuss your next project with our team.
        \nWrite to us: chemicals@saes-group.com<\/p>\n <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":12,"featured_media":2690,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[1],"acf":[],"yoast_head":"\nWhy SPF testing methods matter: ISO 23675 and the future of in vitro sunscreen validation | SAES Chemicals<\/title>\n<meta name=\"description\" content=\"SPF boosting made ethical: learn why ISO 23675 in vitro testing and ZeoSAES\u00ae UV Booster help formulators reduce filters and ensure global compliance.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.saesgetters.com\/chemicals\/why-spf-testing-methods-matter-iso-23675-and-the-future-of-in-vitro-sunscreen-validation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" 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